Dan Melillo

Owner + Principal

Dan is an entrepreneur and investor passionate about building technology that helps businesses run more efficiently and deliver better customer experiences.

He founded Odeza, a leading digital health company specializing in SaaS solutions for patient communications and virtual agents, which was acquired in 2021. Earlier in his career, he held leadership roles at fast-growing tech startups and began his career at GE.

Dan is driven by solving meaningful problems and believes the strongest companies are built by teams who care deeply about their work, their clients, and their communities.

After building and leading startups across multiple industries, Dan founded OpenCanyon Labs as a platform to share that experience with other founders and leadership teams. The firm focuses on strategy, product direction, and growth initiatives, helping companies align around go-to-market execution, organizational design, and fundraising readiness.